False

$show=search/label/May%202022

 


Casgevy UPSC NOTE

 Why in News

  • The U.S. Food and Drug Administration (FDA) approved a pair of gene therapies for sickle cell disease, including the first treatment based on the breakthrough CRISPR gene editing technology.

  • The agency approved Lyfgenia from bluebird bio, and a separate treatment called Casgevy by partners Vertex Pharmaceuticals and CRISPR Therapeutics for the illness.

What is Casgevy 

  • Casgevy AKA exagamglogene autotemcel.

  • It is a groundbreaking gene therapy treatment for sickle cell disease (SCD) and beta thalassemia.

  • These are two serious inherited blood disorders.

  • It utilizes the revolutionary CRISPR-Cas9 gene-editing technology.

Here's how Casgevy works:

  1. Stem cell extraction: The patient's bone marrow is extracted to collect CD34+ hematopoietic stem cells.

  2. Gene editingCRISPR-Cas9 technology is used to edit the defective gene in the stem cells.

3. Stem cell reintroduction: The modified stem cells are then infused back into the patient's bloodstream.

4. Production of healthy red blood cells: The edited stem cells begin producing healthy red blood cells, which alleviate the symptoms of SCD and beta thalassemia.

Benefits of Casgevy:

  • Potentially curative: Casgevy is considered a one-time treatment with the potential to cure these previously incurable diseases.

  • Improved quality of life: By correcting the underlying genetic defect, Casgevy can significantly improve the quality of life for patients by reducing pain, fatigue, and other symptoms.

  • Reduced transfusion dependence: Patients with beta thalassemia often require regular blood transfusions, which can be a burden. Casgevy can reduce or even eliminate the need for transfusions.


COMMENTS

Name

Amritsar,1,Art & Culture,1,August 2023,251,Courses,7,Daily Current Affairs,48,December 2023,189,Disaster Management,2,Environment and Ecology,54,February 2024,188,Foundation Course,1,GDP,1,GEMS Club,1,GEMS Plus,1,Geography,67,Govt Schemes,2,GST,1,History,2,Home,3,IAS Booklist,1,Important News,71,Indian Economy,46,Indian History,2,Indian Polity,56,International Organisation,12,International Relations,58,Invasive Plant,1,January 2024,240,July 2023,281,June 2022,6,June 2023,268,May 2022,17,Mentorship,2,November 2023,169,October 2023,203,Places in News,2,Science & Technology,66,September 2023,205,UPSC CSE,111,
ltr
item
Learnerz IAS | Concept oriented UPSC Classes in Malayalam: Casgevy UPSC NOTE
Casgevy UPSC NOTE
https://lh7-us.googleusercontent.com/DpyRrL7f-arTl_xc3suHkE8ix8bDUnBQZvvmn7UxubOz2ULTxel9KewYtyK9BKSKRNRCD2kEO_gm_Gx_M_KwqPfnuEXdoAJcBMVXXAOMaqwny_R8pgS31YIuzfiHRGeXIRo6kF2qU2dYigakvTkQcA=s2048
https://lh7-us.googleusercontent.com/DpyRrL7f-arTl_xc3suHkE8ix8bDUnBQZvvmn7UxubOz2ULTxel9KewYtyK9BKSKRNRCD2kEO_gm_Gx_M_KwqPfnuEXdoAJcBMVXXAOMaqwny_R8pgS31YIuzfiHRGeXIRo6kF2qU2dYigakvTkQcA=s72-c
Learnerz IAS | Concept oriented UPSC Classes in Malayalam
https://www.learnerz.in/2023/12/casgevy-upsc-note.html
https://www.learnerz.in/
https://www.learnerz.in/
https://www.learnerz.in/2023/12/casgevy-upsc-note.html
true
4761292069385420868
UTF-8
Loaded All Posts Not found any posts VIEW ALL Readmore Reply Cancel reply Delete By Home PAGES POSTS View All RECOMMENDED FOR YOU LABEL ARCHIVE SEARCH ALL POSTS Not found any post match with your request Back Home Sunday Monday Tuesday Wednesday Thursday Friday Saturday Sun Mon Tue Wed Thu Fri Sat January February March April May June July August September October November December Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec just now 1 minute ago $$1$$ minutes ago 1 hour ago $$1$$ hours ago Yesterday $$1$$ days ago $$1$$ weeks ago more than 5 weeks ago Followers Follow THIS PREMIUM CONTENT IS LOCKED STEP 1: Share to a social network STEP 2: Click the link on your social network Copy All Code Select All Code All codes were copied to your clipboard Can not copy the codes / texts, please press [CTRL]+[C] (or CMD+C with Mac) to copy Table of Content