The Role of Cell Geometry in Regeneration: A New Dimension in Morphogenesis
UPSC Relevance
Prelims: Science and Technology - Developments and their applications and effects in everyday life; Awareness in the fields of Bio-technology; General Science (Biology).
Key Highlights from the News
Morphogenesis is the process that helps living organisms regenerate lost body parts and form their shape and structure.
Previously, Stem Cells and genetic pathways were thought to be the main factors (e.g., regeneration of human fingertips, lizard tails).
However, a new study by scientists at IISER Pune in India found that cell geometry and physical cues also play a crucial role in this process.
This discovery was made by observing how the root tip of the Arabidopsis thaliana plant (a mustard-family plant) regenerates after being cut.
It was found that the cells in the cut area, moving away from their usual cube shape, divide in a specific way to help reconstruct the pointed root tip.
Internal mechanical tension within the cells is the primary force behind this cell shape change.
This finding further expands our understanding of the growth and regeneration of living organisms. Physical factors, along with genetic factors, play a significant role.

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