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  • India is taking its first step to introduce Controlled Human Infection Studies (CHIS) for vaccine and treatment development.

  • CHIS involves intentionally exposing healthy volunteers to pathogens in a controlled environment to study diseases like malaria, typhoid, and dengue.

  • CHIS has been a no-go area for India due to ethical concerns, but the Indian Council of Medical Research (ICMR) is set to change this.

  • The ICMR's Bioethics Unit introduced a consensus policy statement supporting the implementation of CHIS in India, addressing ethical issues while ensuring participant protection.

  • India has a high burden of morbidity and mortality from infectious diseases, making the need for novel and cost-effective research methods essential.

  • CHIS offers unique insights into disease pathogenesis and can accelerate the development of medical interventions with smaller sample sizes compared to large clinical trials.

  • The social value of CHIS includes contributions to public health response, healthcare decision-making, policies, economic benefits, pandemic preparedness, and community empowerment.

  • CHIS is a complex area that may require collaborations between researchers, institutions, organizations, and countries to access the right expertise.



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Learnerz IAS | Concept oriented UPSC Classes in Malayalam: CHIS UPSC NOTE
Learnerz IAS | Concept oriented UPSC Classes in Malayalam
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