Nanopore UPSC NOTE

 What is nanopore sequencing and Sturgeon

  • Nanopore sequencing is a third-generation sequencing (TGS) technology.

  • That can sequence long reads of DNA and RNA. 

  • It works by passing DNA or RNA molecules through a protein nanopore.

  • Nanopore is a tiny hole in a protein membrane. Molecule passes through the pore, it causes changes in the electrical current, which are recorded and used to reconstruct the sequence of the molecule.

What is nanopore sequencing and Sturgeon

  • Sturgeon is a deep learning algorithm that is used to classify nanopore sequencing data. 

  • It was developed by researchers at the University Medical Center Utrecht in the Netherlands. 

  • Sturgeon is designed to classify nanopore sequencing data from tumors, and can be used to identify the type of tumor and its aggressiveness.

  • It is still under development, but it has the potential to revolutionize the way that cancer is treated.

What is nanopore sequencing and Sturgeon

Here are some of the benefits of nanopore sequencing:

  • Its can generate reads of DNA and RNA that are thousands of bases long. 

  • Its  makes  ideal for sequencing complex genomes and transcripts.

  • Nanopore sequencing can sequence DNA and RNA in real time. 

  • Nanopore sequencers are portable and relatively inexpensive. 

What is nanopore sequencing and Sturgeon

Here are some of the applications of nanopore sequencing:

  • Used in the sequencing used in the genomes of plants, animals, and microorganisms. 

  • These information can be used to study evolution, disease, and biodiversity.

  • Used in the sequencing of transcriptomes of cells. 

  • Epigenome sequencing

  • Sturgeon is a promising new tool that can be used to classify nanopore sequencing data from tumors. 



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Learnerz IAS | Concept oriented UPSC Classes in Malayalam: Nanopore UPSC NOTE
Nanopore UPSC NOTE
Learnerz IAS | Concept oriented UPSC Classes in Malayalam
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