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Spanish tuberculosis vaccine UPSC NOTE

 Why in news

  • Clinical trials of the Spanish tuberculosis (TB) vaccine MTBVAC have begun in India.

  • Vaccine maker Bharat Biotech is conducting the trials in partnership with Spanish biopharmaceutical company Biofabri.

  • Which is responsible for clinical and industrial development of the vaccine “developed in the laboratory of the University of Zaragoza, with Dr. Brigitte Gicquel of the Pasteur Institute, Paris”.

  • MTBVAC is the only vaccine against tuberculosis undergoing clinical trials based on a genetically modified form of Mycobacterium tuberculosis, the pathogen that causes the disease

  • Unlike the BCG vaccine, the new vaccine contains all “the antigens present in strains that infect humans”. 

  • While trials to evaluate safety and immunogenicity of MTBVAC in India have begun, a pivotal safety, immunogenicity and efficacy trial is planned in 2025, Bharat Biotech said in an announcement coinciding with World Tuberculosis Day.

  • Bharat Biotech will be conducting a Phase 3 trial as Biofabri has completed the Phase 1 and 2 trials in other countries.

  • The MTBVAC vaccine has passed several milestones before entering clinical trials in India, executive chairman Krishna Ella said in a release.

  • Studying the safety, immunogenicity and efficacy of the vaccine in the most populated country and the one with the highest number of cases of the infectious disease is key to continue advancing this vaccine.



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Learnerz IAS | Concept oriented UPSC Classes in Malayalam: Spanish tuberculosis vaccine UPSC NOTE
Spanish tuberculosis vaccine UPSC NOTE
Learnerz IAS | Concept oriented UPSC Classes in Malayalam
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